Department of Veterans Affairs

  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:603157c8a095287470bef3714d3ce59e' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>This study will investigate adjunction pregnenolone for cognitive symptoms and negative symptoms in patients with schizophrenia and schizoaffective disorder.</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:603157c8a095287470bef3714d3ce59e' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Pregnenolone for Cognitive and Negative Symptoms in Schizophrenia</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:709a279cd78ec99afc55c977ba88648a' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>&nbsp;</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:cc7819055cde3194bb3b136bad5cf58d' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:187658b89b9648095f0813c8651bdf76' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Inclusion Criteria:\n<ul>\n<li>Diagnosis: DSM-IV/DSM-IV TR schizophrenia or schizoaffective disorder;</li>\n<li>Gender: Males and Females;</li>\n<li>Age: 25-60;</li>\n<li>Caucasian or Non Caucasian;</li>\n<li>Capable of providing informed consent;</li>\n<li>Duration of illness equal to or greater than one year;</li>\n<li>No change in antipsychotic medication in the previous eight weeks, no change in antipsychotic dose in the previous four weeks;</li>\n<li>No benzodiazepine use in the past twelve hours prior to cognitive testing;</li>\n<li>The patient cohort will be enriched for cognitive symptoms (Composite BACS scores = 0-3 standard deviations below the mean, assessed at the screening visit).</li>\n</ul>\n</p><p> Exclusion Criteria:\n<ul>\n<li>Subjects with a DSM-IV/DSM-IV TR diagnosis of alcohol or substance dependence (other than nicotine) within the last month;</li>\n<li>Subjects with a history of significant head injury/trauma, as defined by one or more of the following:\n<ol>\n<li>Loss of consciousness (LOC) for more than 1 hour,</li>\n<li>Recurring seizures resulting from the head injury,</li>\n<li>Clear cognitive sequelae of the injury,</li>\n<li>Cognitive rehabilitation following the injury;</li>\n</ol>\n</li>\n<li>Subjects with unstable medical illness or neurological illness (seizures, CVA);</li>\n<li>Patients with hormone-sensitive tumors (such as breast, uterine, or prostate cancer);</li>\n<li>Clinically significant abnormalities in physical examination , ECG, or laboratory assessments;</li>\n<li>Pregnant women or women of child-bearing potential, who are either not surgically-sterile or not using appropriate methods of birth control (serum beta-HCG will be performed at baseline, 4 weeks, and 8 weeks to exclude pregnancy);</li>\n<li>Women who are breast-feeding;</li>\n<li>ECT treatment within the last 3 months;</li>\n<li>Use of oral contraceptives or other hormonal supplementation such as estrogen. Although early studies suggested no effects on menstrual cycle, alterations in downstream metabolites of pregnenolone (such as estradiol) could theoretically impact the efficacy of oral contraceptives and/or estrogen replacement. Similarly, it is theoretically possible that pregnenolone could be metabolized to other steroids, resulting in hair, skin, or other steroid-related changes. Since we have determined in our prior study that pregnenolone administration does not result in downstream elevations in DHEA, DHEAS, estradiol, or testosterone, these possibilities may be unlikely;</li>\n<li>Current active suicidal and/or homicidal ideation, intent, or plan;</li>\n<li>Known allergy to study medication.</li>\n</ul>\n</p>', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:187658b89b9648095f0813c8651bdf76' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:1cad65e09205ff0654d5cdc0b9940996' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>The purpose of this study is to test whether treatment with Aripiprazole leads to a reduction in methamphetamine craving and use in patients diagnosed with methamphetamine dependence. Patients presenting at the Omaha VA Medical Center for treatment of methamphetamine dependence, and meet inclusion criteria for the study will be invited to participate. Participation in the study will last for approximately 14 weeks.</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:1cad65e09205ff0654d5cdc0b9940996' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:7097208a6ab9cc0d79adf3b0136048db' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>This study is being conducted to evaluate the benefits of in-the-ear vs. open-fit behind-the-ear hearing aids. We want to learn more about which patients prefer each type, so we can make better choices about which type of hearing aid is best for which patients. Participants in this study will try three different sets of hearing aids for 2 months each, then we will evaluate the benefit of each type.</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:7097208a6ab9cc0d79adf3b0136048db' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Evaluation of Open-Ear Canal and Traditional Custom-Fit Hearing Aids</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:61cd216fca1cfd87f70a6fef8d29ce77' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Hearing loss is the most common service-connected disability nationwide in the VHA system, with hearing aids providing the primary treatment option. Although the benefits of hearing-aid use are clearly established,~16-30% of adults who have hearing aids do not use them. Several factors are believed to result in non-use of traditional hearing aids, including (1) poor fit and comfort, (2) poor cosmetics, (3) whistling feedback, (4) occlusion, and (5) difficulty understanding speech in noise. Recently, the open canal (OC) hearing-aid style has become a viable approach to addressing address many of the problems resulting in non-use of traditional hearing aids, particularly for individuals with mild to moderately-severe hearing loss. Although an OC hearing aid has many potential advantages, there also are potential limitations. For example, the maximum low and high-frequency gain available with an OC fitting is less than that available from traditional custom (TC) hearing-aid fittings, which could result in less than optimal amplification for some individuals. In addition, directional microphone benefits for speech understanding in noise, available with TC fittings, likely will be limited with OC fittings due to the loss of low-frequency gain (Ricketts et al., 2005). Since both OC and TC fittings are appropriate for listeners with mild to moderately-severe hearing losses, evidence is needed to determine which style of hearing aid is preferred by a majority. Currently, OC fittings use a small behind-the-ear (BTE) hearing aid coupled to a thin tube or plastic covered wire ending in a vented &quot;open&quot; eartip. When a TC fitting is used with patients with similar hearing losses, the majority are either an in-the-ear (ITE) or in-the-canal (ITC) .In the proposed study a comparison will be made between OC vs. TC fittings.. In addition to this primary comparison, preference for one of two OC hearing aids, viz., OC instruments with receiver in the ear (OCRITE) and the OC instruments with receiver in the hearing-aid case (OCRIHA), will be determined. The outcomes of the OCRITE, OCRIHA, and TC hearing-aid use related to the factors of: (1) comfort and cosmetics, (2) subjective occlusion, (3) objective occlusion, (4) sound quality for external sounds, (5) feedback, (6) ease of use, (7) audibility, (8) aided signal-to-noise ratio (SNR) benefit, and (9) localization, will be measured in a large (n = 288), randomized-controlled, three-site (Bay Pines, Mountain Home, and Nashville) clinical trial, utilizing a three-period (two months each), cross-over design. A total of 13 variables will be measured for the 9 hearing-aid fitting and style-related factors. At the end of the study, participants will rank order their preferences for the three hearing aid fittings to determine (1) the preferred OC fitting (OCRITE vs. OCRIHA) and (2) whether the highest ranked OC fitting or the TC fitting is preferred. Preferred OC vs. TC difference scores will be calculated for all relevant variables. The ability of the differences scores to predict the preferences of the participants for an OC vs. TC hearing aid will be determined, in order to develop an evidence-based hearing aid selection model.</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:ade1dba132a6d5c1246806d218131bf4' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:22c49af38cbf342e09ca8e0f866a5d23' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Inclusion Criteria:\n<ul>\n<li>Sensorineural hearing loss</li>\n<li>Veteran-adult onset of hearing</li>\n<li>English as first language</li>\n<li>Eligible for VA issued hearing aids</li>\n</ul>\n</p><p> Exclusion Criteria:\n<ul>\n<li>Known neurological, psychiataric disorders, or co-morbid disese that would prevent completion of the study</li>\n<li>Inadequate vision</li>\n<li>Inadequate reading skills</li>\n</ul>\n</p>', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:22c49af38cbf342e09ca8e0f866a5d23' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:13bb1817a61c360412c5f96b11667a16' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>The purpose of this study is to determine whether individualized wound prevention instructions will lengthen the ulcer-free period in veterans with recently healed venous ulcers.</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:13bb1817a61c360412c5f96b11667a16' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Does Use of a Wound After-Care Summary for Patients With a History of Venous Ulcers Lower Recurrence Rate?</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:95f81403d3b2fc36f1caa426051b40fd' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:2ceeb75464294327620e84085aa52464' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Venous ulcer disease is the most common form of lower extremity ulcer, and treatment requires months to years of costly intervention. Preventing venous ulcers from recurring is ideal, however, healing time is variable, possibly due to inadequate patient/clinician communication and surveillance. An aftercare summary is a detailed set of self-care instructions designed to help patients understand and influence preventative factors under their control. They have successfully been used in patients with cardiac disease and are currently being tested to help prevent diabetic foot ulcers. We propose the use of an aftercare summary to help prevent ulcer recurrence in veterans with recently healed venous ulcers.</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:2ceeb75464294327620e84085aa52464' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:c023042ca8d73bfaf9d9f8071bd76359' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Inclusion Criteria:\n<ul>\n<li>Confirmed venous ulcer (ICD-9: 454.0, 454.2, 459.11, 459.13, 459.31, 459.33);</li>\n<li>Documented healing of all lower extremity ulcers;</li>\n<li>Ankle-brachial index (ABI) &gt; 0.8 to rule out arterial insufficiency</li>\n</ul>\n</p><p> Exclusion Criteria:\n<ul>\n<li>Unwilling or unable to sign informed consent;</li>\n<li>No plans to seek care at VA Puget Sound within 6 months;</li>\n<li>Limbs with ulcers or threatened viability</li>\n</ul>\n</p>', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:c023042ca8d73bfaf9d9f8071bd76359' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:3687d45048b30464008852a2007500f4' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Change in quality of life [&nbsp;Time&nbsp;Frame:&nbsp;Telephone call every 2 weeks, on-site visit at 2.5 and 5 months.&nbsp;] [&nbsp;Designated&nbsp;as&nbsp;safety&nbsp;issue:&nbsp;No&nbsp;]</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:3687d45048b30464008852a2007500f4' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:94ae0a649e9dce5f8db2f84cc8d50680' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Change in satisfaction with care [&nbsp;Time&nbsp;Frame:&nbsp;Telephone call every 2 weeks, on-site visit at 2.5 and 5 months.&nbsp;] [&nbsp;Designated&nbsp;as&nbsp;safety&nbsp;issue:&nbsp;No&nbsp;]</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:94ae0a649e9dce5f8db2f84cc8d50680' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Adherence with self-management goals [&nbsp;Time&nbsp;Frame:&nbsp;Telephone call every 2 weeks, on-site visit at 2.5 and 5 months.&nbsp;] [&nbsp;Designated&nbsp;as&nbsp;safety&nbsp;issue:&nbsp;No&nbsp;]</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:a73646251acadf14fed1caafe78ff473' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:9ae291e015be0447f1166eb085c004a3' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>The purpose of this study is to evaluate and compare treatment with fiber and loperamide for fecal incontinence.</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:9ae291e015be0447f1166eb085c004a3' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:388f6b98a010903d9e162eb334ef2d82' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>The study is designed to examine the effectiveness of a computer-based auditory training program to improve the benefits received by individuals who wear hearing aids. The study will involve 3 groups - a computer-based training group, an active listening group which will involve listening to books on CD, and a placebo group that receives no additional treatment.</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:388f6b98a010903d9e162eb334ef2d82' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Supplementing Hearing Aids With Computerized Auditory Training</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:869245201bf7ccfa2253ff977b2c1ccc' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:843bac6bec018379063ba2b9b1ae2a9c' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>This proposed study is a multi-site, single-masked (blinded), randomized controlled, parallel group clinical trial to assess the effectiveness of an at home PC-based auditory training as a supplement to standard-of-care hearing-aid intervention in veterans treated for hearing loss, with or without previous hearing-aid experience. The participants will be assigned randomly to one of three groups, with hearing-aid use stratified within the groups: (1) Group 1, HA+AT, in which the participants will receive standard-of-care hearing-aid intervention (HA) and complete the four-week LACE auditory training program (AT); (2) Group 2, HA, with the participants receiving only standard-of-care hearing-aid intervention (HA); and (3) Group 3, HA+DL, in which the participants will receive standard-of-care hearing-aid intervention (HA) and complete four-weeks of placebo auditory training, consisting of directed listening (DL) to books-on-tape. The participants in each group will attend four test sessions. During Session 1 the informed consent process will be completed, baseline assessments will be made to ensure that the participants meet the study inclusion criteria (page 52), testing of predictor variables (page 57-58) will be completed, and all hearing aids will be assessed for correct functionality (page 53). The participants then will be assigned randomly to a study group. Session 2 will occur four weeks after Session 1. During Session 2, baseline performance on the outcome measures will be assessed (page 54-57), as will performance on the predictor variables. Following testing, the participants in Groups 1 and 3 will receive training in the use of the AT or DL programs. Session 3 will occur at the end of the 4-week experimental training period. During Session 3 all participants will be retested on the outcome measures to assess short-term intervention outcomes. During Session 4, which will occur at seven-months post-study enrollment (i.e., six-months post training completion for Groups 1 and 3), all participants will be retested on all outcome measures to examine the long-term outcomes. In Sessions 2-4, the stability of hearing-aid function will be assessed through electroacoustic measures.</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:843bac6bec018379063ba2b9b1ae2a9c' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:a14e3020fdd361d4fea049274a747e6a' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Inclusion Criteria:\n<ol>\n<li>adult onset hearing loss,</li>\n<li>English as the first language,</li>\n<li>bilateral, symmetric, sensorineural hearing loss,</li>\n<li>average audiometric thresholds for 500, 1000, and 2000 Hz less than 50-dB HL in either ear,</li>\n<li>aided speech recognition in quiet of 40% binaurally,</li>\n<li>appropriate cognitive skills assessed using the Mini Mental State Exam (Folstein et al., 1975) with age/education norms (Crum et al., 1993),</li>\n<li>no known neurological, psychiatric disorders, or co-morbid diseases that would prevent completion of the study as determined by chart review,</li>\n<li>adequate vision to participate in the study as determined with the Smith-Kettlewell Institute Low Luminance (SKILL) Card,</li>\n<li>eligible for VA-issued hearing aids.</li>\n</ol>\n</p><p> Exclusion Criteria:</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:a14e3020fdd361d4fea049274a747e6a' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:f05457adecad7ce1396020e1a52f4895' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Medically ill patients with Congestive Heart Failure (CHF) and Chronic Obstructive Pulmonary Disease (COPD) are at increased risk for developing symptoms of anxiety and depression and are among the least frequent users of mental health services and treatments. To address the needs of chronically ill patients, we created a time-limited psychosocial intervention to maximize treatment benefits and improve the efficiency and ability of mental health care practitioners to provide services within medical care settings. This study is separated into two randomized study groups. The first group of participants will receive the ACCESS intervention immediately. The second group of participants will be followed for a period of 6 months. After a period of 6 months, those who continue to have symptoms of depression and/or anxiety will be offered the ACCESS intervention.</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:f05457adecad7ce1396020e1a52f4895' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:61007c76e701cf2c786390d4d22d4b97' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Improving Quality Of Life For Chronically Ill Patients Using Education Support And Skills; A Randomized Controlled Mental Trial</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:61007c76e701cf2c786390d4d22d4b97' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>&nbsp;</p>\n', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:cc7819055cde3194bb3b136bad5cf58d' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Inclusion Criteria:\n<ol>\n<li>Age 18+;</li>\n<li>Confirmation of CHF or COPD diagnosis according to medical chart review;</li>\n<li>Ongoing symptoms of functional limitations due to CHF (NYHA classification of II , III, or IV as obtained by telephone interview) or COPD (Score of 3 or greater on the Medical Research Council Dyspnoea Scale [MRC] as obtained by telephone interview);</li>\n<li>Eligible patients must have clinically significant symptoms of either anxiety and/or depression as measured using patient self report questionnaires. Clinical cutoff scores for depression will be based on the Beck Depression Inventory - Second Edition (scores of 14 or more) while anxiety cutoffs will be determined using the State-Trait Anxiety Inventory - trait subscale (score of 40 or greater);</li>\n<li>Eligible patients will be English-speaking, as this intervention has not yet been translated to any other language.</li>\n</ol>\n</p><p> Exclusion Criteria:\n<ol>\n<li>History of substance abuse, bipolar disorder, psychosis or active suicidal intent (obtained from standardized structured clinical interview);</li>\n<li>NYHA class I, or MRC levels 1 and 2. Class 1 CHF patients and Level 1 and 2 COPD patients (by definition) will have no significantly limiting CHF or COPD symptoms. This information will be obtained through patient self-report of CHF and COPD symptoms;</li>\n<li>Mental status examination score in the cognitively impaired range on an established 6-item screen;</li>\n<li>Inability to provide informed consent or severe physical limitations restricting completion of the study protocol (e.g. vision, hearing, or physical functioning);</li>\n<li>Non-English speaking patients will be excluded from participation, as this intervention has not yet been translated to any other language.</li>\n</ol>\n</p>', created = 1283574239, expire = 1283660639, headers = '', serialized = 0 WHERE cid = '1:7f2351704df2d99eb57e8f12267d1645' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>The Veterans Health Administration (VHA) has stated the need for a brief screening instrument that can assist with the triage of the enormous number of returning OIF/OEF veterans with concussion. The investigators combined selected neurological and brief cognitive tests to develop an instrument called, &quot;Pincus Repeatable Objective Neurobehavioral Evaluation&quot; (PRONE). PRONE takes only 15-20 minutes to administer with immediate results. In a previous study, PRONE was able to predict periventricular white matter disease (PWMD) visible on MRI scans with 91% sensitivity and 76% specificity. Thus, PRONE has shown sensitivity to, and specificity for, white matter abnormalities. Given that white matter abnormalities are the most common type of injury in mTBI, it is probable that PRONE could be sensitive to traumatic axonal injury (TAI) in TBI. Advanced neuroimaging measures, such as diffusion tensor imaging, will be used to help validate PRONE. If validated as a screening tool for OIF/OEF veterans with concussion, PRONE could reduce evaluation and associated waiting times and accelerate the initiation of treatment or case management. These benefits would be expected to increase veteran quality of life and satisfaction with care.</p>\n', created = 1283574240, expire = 1283660640, headers = '', serialized = 0 WHERE cid = '1:022fe525aa754b17a2def150a18a5164' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Many older subjects experience difficulty in understanding speech in noisy environments. Part of this problem is related to changes that occur in the ear with age and compromise the hearing of high-pitched sounds. Another part of the problem with speech understanding relates to changes with age in the neural circuits of the brain that process different speech sounds. Evidence suggests that these changes in neural circuits are particularly large if hearing loss is present. Thus, while hearing aids may help compensate for hearing deficits by amplifying speech sounds, additional treatment is necessary to restore optimal neural connections in the brain so that speech sounds can be accurately distinguished from each other. We are developing PC-based training programs in an attempt to restore optimal neural connections. The current randomized trial will evaluate whether two months of training to improve the ability to discriminate different consonant sounds in noise will also improve the understanding of continuous speech and enhance auditory memory and other high-level auditory functions.</p>\n', created = 1283574240, expire = 1283660640, headers = '', serialized = 0 WHERE cid = '1:12969419a5741a0d30f30f313f30371f' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>The purpose of this study is to evaluate whether a smoking cessation telephone care coordination program is effective and feasible in VA Mental Health Clinics.</p>\n', created = 1283574240, expire = 1283660640, headers = '', serialized = 0 WHERE cid = '1:51db5b7bfb0727622170d3ca9786e765' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Telephone Care Coordination for Smokers in Mental Health Clinics</p>\n', created = 1283574240, expire = 1283660640, headers = '', serialized = 0 WHERE cid = '1:ddcb2650abc7e10a706515ba255d2546' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:d7875faaa97154bb5194021a177cab1f' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Smoking is the leading preventable cause of death in the United States and is a particular problem among VA users and among persons with a diagnosed mental illness. The prevalence of smoking among VA mental health patients has remained high, in part because smoking cessation treatment rates have remained low. Telephone-based counseling represents the most feasible approach to increasing smoking cessation treatment among VA patients. The approach used in this study has been used very effectively in a primary care-based population that includes a large percentage of mental health patients. This project would target the program specifically at patients seen in VA Mental Health Clinics.</p>\n', created = 1283574240, expire = 1283660640, headers = '', serialized = 0 WHERE cid = '1:d7875faaa97154bb5194021a177cab1f' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Inclusion Criteria: Smokers who are referred from Mental Health Clinics in VA VISNs 1 and 3. Patients must have access to a telephone and a regular mailing address. Exclusion Criteria: No access to a telephone, no mailing address, not referred from a VISN 1 or VISN 3 Mental Health provider.</p>\n', created = 1283574240, expire = 1283660640, headers = '', serialized = 0 WHERE cid = '1:e00f933c51ab929acf775a98174cdd73' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>30-day point prevalence abstinence rate at 2-months (i.e., end of treatment) [&nbsp;Time&nbsp;Frame:&nbsp;2 months after enrollment&nbsp;] [&nbsp;Designated&nbsp;as&nbsp;safety&nbsp;issue:&nbsp;No&nbsp;]</p>\n', created = 1283574240, expire = 1283660640, headers = '', serialized = 0 WHERE cid = '1:28df3cebe30973c75391e8b8f580aac7' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Quit attempt rate [&nbsp;Time&nbsp;Frame:&nbsp;2 and 6 months after enrollment&nbsp;] [&nbsp;Designated&nbsp;as&nbsp;safety&nbsp;issue:&nbsp;No&nbsp;]</p>\n', created = 1283574240, expire = 1283660640, headers = '', serialized = 0 WHERE cid = '1:2d952d430b8c681b443977efd9d46d8d' in /persistent/html/includes/cache.inc on line 109.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: SELECT data, created, headers, expire, serialized FROM cache_filter WHERE cid = '1:ed320f3482212fa3be22def452a4d14d' in /persistent/html/includes/cache.inc on line 26.
  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>Rate of use of smoking cessation medications (i.e., treatment rate) [&nbsp;Time&nbsp;Frame:&nbsp;2 and 6 months after enrollment&nbsp;] [&nbsp;Designated&nbsp;as&nbsp;safety&nbsp;issue:&nbsp;No&nbsp;]</p>\n', created = 1283574240, expire = 1283660640, headers = '', serialized = 0 WHERE cid = '1:ed320f3482212fa3be22def452a4d14d' in /persistent/html/includes/cache.inc on line 109.
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  • user warning: Table './intheclinic/cache_filter' is marked as crashed and should be repaired query: UPDATE cache_filter SET data = '<p>VA site-level performance rates on the VA tobacco performance measures [&nbsp;Time&nbsp;Frame:&nbsp;Quarterly after study implementation&nbsp;] [&nbsp;Designated&nbsp;as&nbsp;safety&nbsp;issue:&nbsp;No&nbsp;]</p>\n', created = 1283574240, expire = 1283660640, headers = '', serialized = 0 WHERE cid = '1:a4c938d4d448abb02462525f3eaab6f0' in /persistent/html/includes/cache.inc on line 109.

Pregnenolone for Cognitive and Negative Symptoms in Schizophrenia

Trial phase: 
Phase II
Recruitment status: 
Not yet recruiting

This study will investigate adjunction pregnenolone for cognitive symptoms and negative symptoms in patients with schizophrenia and schizoaffective disorder.

Background information
Trial ID: 
NCT00728728
Other unique IDs: 
MHBB-012-07F
Official title: 

Pregnenolone for Cognitive and Negative Symptoms in Schizophrenia

Detailed description: 

 

Number to be enrolled: 
88 patients

Aripiprazole for Methamphetamine Dependence: Double Blind Placebo Trial

The purpose of this study is to test whether treatment with Aripiprazole leads to a reduction in methamphetamine craving and use in patients diagnosed with methamphetamine dependence. Patients presenting at the Omaha VA Medical Center for treatment of methamphetamine dependence, and meet inclusion criteria for the study will be invited to participate. Participation in the study will last for approximately 14 weeks.

Background information
Other unique IDs: 
CDA-2-017-08S

Evaluation of Open-Canal Behind-the-Ear Hearing Aids and Traditional In-the-Ear Hearing Aids.

Recruitment status: 
Not yet recruiting

This study is being conducted to evaluate the benefits of in-the-ear vs. open-fit behind-the-ear hearing aids. We want to learn more about which patients prefer each type, so we can make better choices about which type of hearing aid is best for which patients. Participants in this study will try three different sets of hearing aids for 2 months each, then we will evaluate the benefit of each type.

Background information
Trial ID: 
NCT00727909
Other unique IDs: 
C6288R
Official title: 

Evaluation of Open-Ear Canal and Traditional Custom-Fit Hearing Aids

Detailed description: 

Hearing loss is the most common service-connected disability nationwide in the VHA system, with hearing aids providing the primary treatment option. Although the benefits of hearing-aid use are clearly established,~16-30% of adults who have hearing aids do not use them. Several factors are believed to result in non-use of traditional hearing aids, including (1) poor fit and comfort, (2) poor cosmetics, (3) whistling feedback, (4) occlusion, and (5) difficulty understanding speech in noise.

Number to be enrolled: 
288 patients

Study of Individualized Wound Prevention Instruction to Prevent Venous Ulcer Development

Trial phase: 
Phase I
Recruitment status: 
Active, not recruiting

The purpose of this study is to determine whether individualized wound prevention instructions will lengthen the ulcer-free period in veterans with recently healed venous ulcers.

Background information
Trial ID: 
NCT00727701
Other unique IDs: 
08-246
Official title: 

Does Use of a Wound After-Care Summary for Patients With a History of Venous Ulcers Lower Recurrence Rate?

Detailed description: 

Venous ulcer disease is the most common form of lower extremity ulcer, and treatment requires months to years of costly intervention. Preventing venous ulcers from recurring is ideal, however, healing time is variable, possibly due to inadequate patient/clinician communication and surveillance. An aftercare summary is a detailed set of self-care instructions designed to help patients understand and influence preventative factors under their control. They have successfully been used in patients with cardiac disease and are currently being tested to help prevent diabetic foot ulcers.

Number to be enrolled: 
72 patients

Efficacy and Mechanisms of Pharmacologic Treatment of Fecal Incontinence

The purpose of this study is to evaluate and compare treatment with fiber and loperamide for fecal incontinence.

Background information
Other unique IDs: 
B6126W

Supplementing Hearing Aids With Computerized Auditory Training

Recruitment status: 
Recruiting

The study is designed to examine the effectiveness of a computer-based auditory training program to improve the benefits received by individuals who wear hearing aids. The study will involve 3 groups - a computer-based training group, an active listening group which will involve listening to books on CD, and a placebo group that receives no additional treatment.

Background information
Trial ID: 
NCT00727337
Other unique IDs: 
C6303R
Official title: 

Supplementing Hearing Aids With Computerized Auditory Training

Detailed description: 

This proposed study is a multi-site, single-masked (blinded), randomized controlled, parallel group clinical trial to assess the effectiveness of an at home PC-based auditory training as a supplement to standard-of-care hearing-aid intervention in veterans treated for hearing loss, with or without previous hearing-aid experience.

Number to be enrolled: 
288 patients
Acronym: 
LACE

Adjusting to Chronic Conditions Using Education Support and Skills

Recruitment status: 
Recruiting

Medically ill patients with Congestive Heart Failure (CHF) and Chronic Obstructive Pulmonary Disease (COPD) are at increased risk for developing symptoms of anxiety and depression and are among the least frequent users of mental health services and treatments. To address the needs of chronically ill patients, we created a time-limited psychosocial intervention to maximize treatment benefits and improve the efficiency and ability of mental health care practitioners to provide services within medical care settings. This study is separated into two randomized study groups. The first group of participants will receive the ACCESS intervention immediately. The second group of participants will be followed for a period of 6 months. After a period of 6 months, those who continue to have symptoms of depression and/or anxiety will be offered the ACCESS intervention.

Background information
Trial ID: 
NCT00727155
Other unique IDs: 
H23264
Official title: 

Improving Quality Of Life For Chronically Ill Patients Using Education Support And Skills; A Randomized Controlled Mental Trial

Detailed description: 

 

Number to be enrolled: 
50 patients
Acronym: 
ACCESS

Validation of Brief Objective Neurobehavioral Detectors (BOND) in Mild TBI

The Veterans Health Administration (VHA) has stated the need for a brief screening instrument that can assist with the triage of the enormous number of returning OIF/OEF veterans with concussion. The investigators combined selected neurological and brief cognitive tests to develop an instrument called, "Pincus Repeatable Objective Neurobehavioral Evaluation" (PRONE). PRONE takes only 15-20 minutes to administer with immediate results. In a previous study, PRONE was able to predict periventricular white matter disease (PWMD) visible on MRI scans with 91% sensitivity and 76% specificity. Thus, PRONE has shown sensitivity to, and specificity for, white matter abnormalities. Given that white matter abnormalities are the most common type of injury in mTBI, it is probable that PRONE could be sensitive to traumatic axonal injury (TAI) in TBI. Advanced neuroimaging measures, such as diffusion tensor imaging, will be used to help validate PRONE. If validated as a screening tool for OIF/OEF veterans with concussion, PRONE could reduce evaluation and associated waiting times and accelerate the initiation of treatment or case management. These benefits would be expected to increase veteran quality of life and satisfaction with care.

Background information
Other unique IDs: 
SHP 08-167
01133

PC-Based Rehabilitation of Auditory Function

Many older subjects experience difficulty in understanding speech in noisy environments. Part of this problem is related to changes that occur in the ear with age and compromise the hearing of high-pitched sounds. Another part of the problem with speech understanding relates to changes with age in the neural circuits of the brain that process different speech sounds. Evidence suggests that these changes in neural circuits are particularly large if hearing loss is present. Thus, while hearing aids may help compensate for hearing deficits by amplifying speech sounds, additional treatment is necessary to restore optimal neural connections in the brain so that speech sounds can be accurately distinguished from each other. We are developing PC-based training programs in an attempt to restore optimal neural connections. The current randomized trial will evaluate whether two months of training to improve the ability to discriminate different consonant sounds in noise will also improve the understanding of continuous speech and enhance auditory memory and other high-level auditory functions.

Background information
Other unique IDs: 
C4739R

Telephone Care Coordination for Smokers in VA Mental Health Clinics

Recruitment status: 
Not yet recruiting

The purpose of this study is to evaluate whether a smoking cessation telephone care coordination program is effective and feasible in VA Mental Health Clinics.

Background information
Trial ID: 
NCT00724308
Other unique IDs: 
SDP 07-034
Official title: 

Telephone Care Coordination for Smokers in Mental Health Clinics

Detailed description: 

Smoking is the leading preventable cause of death in the United States and is a particular problem among VA users and among persons with a diagnosed mental illness. The prevalence of smoking among VA mental health patients has remained high, in part because smoking cessation treatment rates have remained low. Telephone-based counseling represents the most feasible approach to increasing smoking cessation treatment among VA patients. The approach used in this study has been used very effectively in a primary care-based population that includes a large percentage of mental health patients.

Number to be enrolled: 
10000 patients
Acronym: 
TeleQuit MH
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